Cyclosporin A-Derivative 1 Free base ( )

Catalog No. M30104 CAS No. 286852-20-8

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Product Name

Cyclosporin A-Derivative 1 Free base
Note

Research use only, not for human use.
Brief Description

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1.
Description

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1.(In Vitro):Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporine A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate.
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Fabrice Gallou, et al. Process for the manufacture of cyclic undecapeptides. WO 2013167703 A1.

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